How To Get Rid Of Cellulite In Time For Summer

Cellulite is a massive skincare concern for many as it affects 80% of women.

While the exact molecular mechanisms of cellulite is not fully understood by scientists, cellulite is described as a complex skin disorder that involves the bulging of subcutaneous fat into the middle layer of the skin (the dermis). This results in structural, inflammatory, and biochemical changes in the skin, as well as dimpling and lumps on the skin’s surface.

While cellulite cannot be cured, it is possible to dramatically reduce its appearance. ​ To date, most remedies are either complete ineffective as they are not able to reach target sites within the skin or fat tissue, or they are extremely expensive, invasive, and inconsistent in their results.

Reducing cellulite involves altering the fat tissue, skin collagen content and connective tissue. ​ Next generation technologies include highly bioavailable nutraceutical supplements and cosmeceutical skincare technologies that can do just this.

Dermoi’s Chief Scientific Officer Eve Casha, MSc in Pharmaceutical Formulation, outlines clinically-proven technologies for improvement of cellulite.

Skinade Cellulite

Skinade Cellulite provides a multifaceted approach to the improvement of cellulite. This is due to its highly bioavailable liquid, micro solid in suspension, and powder activator formulation, which introduces 19 actives deep into the skin. ​ It increases dermal integrity, hormone balance, microcirculation, and metabolism while reducing water retention, inflammation, and protrusion of fat tissue into the skin.

Skinade Cellulite combines scientifically studied collagen peptides, which act on fibroblast cells to stimulate dermal remodelling, with a patented, plant-based form of superoxide dismutase called TSC active. ​ TSC active reveals firmer, smoother skin with reduced lumpiness and dimpling. It has shown a visible reduction in cellulite by 10% in 28 days in randomized, double blind, placebo-controlled clinical trials with 41 women. ​

Evenswiss

Evenswiss is the creator of patented cosmeceutical and pharmaceutical technology Dermatopoietin.

Dermatopoietin is equivalent to a signaling protein naturally found in the skin (human epidermal cytokine interleukin 1-alpha). ​ It generates a strong signaling cascade from the surface of the skin into the dermis to stimulate intense regeneration. ​ Dermatopoietin thickens the skin as it increases collagen, elastin, and hyaluronic acid by up to 90% in 2 weeks.

Dermatopoietin strengths the skin and increases in integrity of its dermal tissue, and therefore, it reduces fat bulging into the skin and the appearance of cellulite. It has been investigated for cellulite in randomized, double-blind, placebo-controlled clinical trials with 20 women. Within 8 weeks, the skin structure was strengthened and the hypodermal- dermal interface was flattened by 22% in 4 weeks. This reduced fat protrusion into the dermis and appearance of cellulite.

The stronger and lighter the colour the denser the proteins. Visible are the layers of keratin in the epidermis (yellow band at left) and of collagen in the dermis (wide green layer). Black pixels represent proteoglycans, lipids and water.

References & Clinical Trials

B. Lemaire, S. Le Quéré & D. Lacan, "Clinical trial of a natural and bioactive melon SuperOxide Dismutase on cellulite," Phytothérapie, 2015.

M. Goldman and D. Hexsel, “Cellulite: Pathophysiology and Treatment,” Informa Healthcare, 2009. ​

MP Francisco et al., “Evidence-Based treatment for gynoic lipodystrophy: A review of the recent literature,” J cosmet dermatol, 2018.

P. Schoch & I. Polmytkin, "Synergistic peptide action revitalises skin and hair," Personal Care, 2010.

Z. Draelos, "The disease of cellulite," J cosmet dermatol, 2005. ​

Press Contact

Nicole Gonzalez, Head of Public Relations

nicole@dermoi.com